ImportancePrevious studies of post-acute COVID-19 syndrome have focused on critical cases with severe disease. However, most cases are mild to moderate in disease severity.ObjectiveWe aimed to examine cognitive outcomes in cases of non-critical, mild-to-moderate COVID-19. Design, Setting, and Participants: In this cross-sectional study, we enrolled 72 adults aged 22 to 65 years in Central Texas who had non-critical, mild-to-moderate COVID-19 infection between 13 January 2021 and 20 April 2021.Main Outcomes and MeasuresWe remotely administered cognitive-behavioral testing to determine the frequency of (...) cognitive impairment and examine demographic, clinical, and psychosocial contributors to impairment.ResultsThe frequency of objective cognitive impairment was 40%. The largest number of participants showed impairment on a measure of executive functioning. Attention and processing speed was more impaired in males. Males endorsed lower adherence to social distancing guidelines, which was in turn associated with cognitive impairment across participants. Younger age was correlated with impairment but was also associated with racial/ethnic minority status and increased psychological symptoms. Moderate COVID-19 severity was associated with attention/processing speed impairment, increased pain, and higher number of COVID-19 symptoms.Conclusion and RelevanceMild or moderate COVID-19 infection may be associated with cognitive impairments, especially in the domain of executive functioning. A subgroup of younger individuals may be more vulnerable to cognitive and psychosocial effects of COVID-19.HighlightsQuestion: How frequent is cognitive impairment among non-critical, mild-to-moderate COVID-19 survivors?FindingsIn this cross-sectional study of 72 adults, 40% demonstrated cognitive impairment, particularly in executive function.MeaningNeurologic sequelae, such as cognitive impairment, may be common following COVID-19 infection. (shrink)

The human fovea is known for its distinctive pit‐like appearance, which results from the displacement of retinal layers superficial to the photoreceptors cells. The photoreceptors are found at high density within the foveal region but not the surrounding retina. Efforts to elucidate the mechanisms responsible for these unique features have ruled out cell death as an explanation for pit formation and changes in cell proliferation as the cause of increased photoreceptor density. These findings have led to speculation that mechanical forces (...) acting within and on the retina during development underly the formation of foveal architecture. Here we review eye morphogenesis and retinal remodeling in human embryonic development. Our meta‐analysis of the literature suggests that fovea formation is a protracted process involving dynamic changes in ocular shape that start early and continue throughout most of human embryonic development. From these observations, we propose a new model for fovea development. (shrink)

BackgroundNarrative medicine is a well-recognized and respected approach to care. It is now found in medical school curricula and widely implemented in practice. However, there has been no analysis of the perception and usage of narrative medicine across different medical specialties and whether there may be unique recommendations for implementation based upon specialty. The aims of this study were to explore these gaps in research.MethodsFifteen senior physicians who specialize in internal medicine, pediatrics, or surgery (5 physicians from each specialty) were (...) interviewed in a semi-structured format about the utilization, benefits, drawbacks (i.e., negative consequences), and roles pertaining to narrative medicine. Qualitative content analysis of each interview was then performed.ResultsThree themes emerged from our analysis: roles, practice, and outcomes. Through these themes we examined the importance, utilization, barriers, benefits, and drawbacks of narrative medicine. There was consensus that narrative medicine is an important tool in primary care. Primary care physicians (general internists and general pediatricians) also believed that narrative medicine is not as important for non-primary care providers. However, non-primary care providers (surgeons) generally believed narrative medicine is valuable in their practice as well. Within specialties, providers’ choice of language varied when trying to obtain patients’ narratives, but choice in when to practice narrative medicine did not differ greatly. Among specialties, there was more variability regarding when to practice narrative medicine and what barriers were present. Primary care physicians primarily described barriers to eliciting a patient’s narrative to involve trust and emotional readiness, while surgeons primarily described factors involving logistics and patient data as barriers to obtaining patients’ narratives. There was broad agreement among specialties regarding the benefits and drawbacks of narrative medicine.ConclusionsThis study sheds light on the shared and unique beliefs in different specialties about narrative medicine. It prompts important discussion around topics such as the stereotypes physicians may hold about their peers and concerns about time management. These data provide some possible ideas for crafting narrative medicine education specific to specialties as well as future directions of study. (shrink)

How the rational imagination develops remains an open question. The ability to imagine emerges early in childhood, well before the ability to reason counterfactually, and this suggests that imaginative thought may facilitate later counterfactual ability. In addition, developmental data indicate that inhibitory control may also play a role in the ability to reason counterfactually.

Attentional control theory suggests that high cognitive demands impair the flexible deployment of attention control in anxious adults, particularly when paired with external threats. Extending this...

An ongoing debate in affective science concerns whether certain discrete, “basic” emotions have evolutionarily based signals that are easily, universally, and innatel...

This article offers a critique of the recently revised BMA guidance on routine neonatal male circumcision and seeks to challenge the assumptions underpinning the guidance which construe this procedure as a matter of parental choice. Our aim is to problematise continued professional willingness to tolerate the non-therapeutic, non-consensual excision of healthy tissue, arguing that in this context both professional guidance and law are uncharacteristically tolerant of risks inflicted on young children, given the absence of clear medical benefits. By interrogating historical (...) medical explanations for this practice, which continue to surface in contemporary justifications of non-consensual male circumcision, we demonstrate how circumcision has long existed as a procedure in need of a justification. We conclude that it is ethically inappropriate to subject children—male or female—to the acknowledged risks of circumcision and contend that there is no compelling legal authority for the common view that male circumcision is lawful. (shrink)

The process by which emotion concepts are learned is largely unexplored. Hoemann, Devlin, and Barrett and Shablack, Stein, and Lindquist argue that emotion concepts are learned throug...

This is a critical introduction to modern French philosophy, commissioned from one of the liveliest contemporary practitioners and intended for an English-speaking readership. The dominant 'Anglo-Saxon' reaction to philosophical development in France has for some decades been one of suspicion, occasionally tempered by curiosity but more often hardening into dismissive rejection. But there are signs now of a more sympathetic interest and an increasing readiness to admit and explore shared concerns, even if these are still expressed in a very different (...) idiom and intellectual context. Vincent Descombes offers here a personal guide to the main movements and figures of the last forty-five years. He traces over this period the evolution of thought from a generation preoccupied with the 'three H's' - Hegel, Husserl and Heidegger, to a generation influenced since about 1960 by the 'three masters of suspicion' - Marx, Nietzsche and Freud. In this framework he deals in turn with the thought of Sartre, Merleau-Ponty, the early structuralists, Foucault, Althusser, Serres, Derrida, and finally Deleuze and Lyotard. The 'internal' intellectual history of the period is related to its institutional setting and the wider cultural and political context which has given French philosophy so much of its distinctive character. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:CONSTRUCTING AND RECONSTRUCTING THE HUMAN BODY Scriptural Anthropology T:ODAY BIOETHICAL ISSUES are much discussed by heologians. Yet they make little use of the Bible in olving these problems. Why? Is it because these bioethical issues are so new it seems unlikely the Bible has much to say about them? Rather it is because many suppose that scholars have shown the Bible's moral teaching to be so historically conditioned that (...) it cannot be normative for" modern man" but only paranetic, i.e. it exhorts and motivates us to do good and avoid evil but provides no concrete norms of good and evil still valid today. Such norms must be supplied by philosophical ethics and the empirical sciences. Hence, in moral argument we should avoid Biblical" proof-texting." 1 The recent development of " canon criticism " provides, I believe, a way out of this impasse.2 The doctrine of Biblical inspiration means that although the Council of Trent declared the Bible inspired "in all its parts ",3 yet this guarantee of inerrancy applies not to these parts taken in "proof-texting" iso1 For a collection of current essays on this subjects see Charles E. Curran and Richard A. McCormick, S.J., eds. The Use of Scripture mMoral Theology (Readings in Moral Theology, No. 4) (New York: Paulist Press, 1984) and Robert J. Daly, S.J., et al. Christian Biblical Ethics from Biblical Revelation to Contemporary Christian Praxis, Method and Content (New York: Paulist Press, 1984) for a more systematic argument. For my own position see, "The Development of Doctrine about Sin, Conversion, and the Following of Christ" in Moral Theology Today: Certitudes and Doubts (St. Louis: Pope John Center, 1984) p. 46-64. 2 See Brevard S. Childs, The New Testament as Canon (Philadelphia: Fortress Press, 1984), pp. 3-47. 3 Council of Trent, Session IV, DS 1504, Vatican II, Dei Verbum, n. 11. 501 502 BENEDICT M. ASHLEY, O.P. lation nor merely in their context within a given book of the Bible, but in their ultimate context within the total Canon. Consequently, seriously to view the Bible from the perspective of a " historicist " rather than a " classical world view " (as Bernard Lonergan urged us to do 4) we must not leave the concrete moral teaching of the Scripture on the shelf of the pa.st. Instead let's use a hermeneutic by which God's Word revealed in history truly illuminates today's problems. Scripture and the Construction of the Human Person Today we are concerned about problems of artificial human reproduction and of genetic engineering. Does the Bible cast any light on these puzzles? To ask about reconstructing humans, we must first ask how God constructed them. Through much of its history Catholic theology read the Bible through the eyes of Platonism because this seemed to make the Gospel intelligible and credible to the Greco-Roman world. Perhaps it was this Platonic theology that Lonergan was thinking about when he spoke of " the classical worldview " with its neglect of human historicity. Platonism helped theology defend the "primacy of the spiritual" and especially the dignity and immortality of the human spirit. But it also favored a non-biblical dualism which identified the true human person with the soul and considered the body as its tomb.5 If we shelve this Platonic theology and seek a less dualistic, more historicist anthropology, we discover the first chapters of Genesis wonderfully provide such an anthropology as the basis of a moral Instruction or Torah.6 This Torah forms the cove4 Bernard Lonergan, "The Transition from a Classicist World-View to Historical Mindedness" (1966) in Second Collection, ed. by W. F. K. Ryan and B. J. Tyrrell (London: Darton, Longmans, Todd, 1974), pp. 1-9. 5 For an extensive discussion of this history see my Theologies of the Body: Humanist and Christian (Braintree, Mass.: Pope John Center, 1985), pp. 101250. 6 Isaac M. Kikawanda and Arthur Quinn, Before Abraham Was (Nashville, Tenn.: Abngidon Press, 1985), discounting the Documentary Hypothesis not from a conservative but from an advanced literary point of view, have pro- CONSTRUCTING/RECONSTRUCTING THE HUMAN BODY 503 nant foundation of both Old and New Testament around which the whole Canon takes... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:CONSTRUCTING AND RECONSTRUCTING THE HUMAN BODY Scriptural Anthropology T:ODAY BIOETHICAL ISSUES are much discussed by heologians. Yet they make little use of the Bible in olving these problems. Why? Is it because these bioethical issues are so new it seems unlikely the Bible has much to say about them? Rather it is because many suppose that scholars have shown the Bible's moral teaching to be so historically conditioned that (...) it cannot be normative for" modern man" but only paranetic, i.e. it exhorts and motivates us to do good and avoid evil but provides no concrete norms of good and evil still valid today. Such norms must be supplied by philosophical ethics and the empirical sciences. Hence, in moral argument we should avoid Biblical" proof-texting." 1 The recent development of " canon criticism " provides, I believe, a way out of this impasse.2 The doctrine of Biblical inspiration means that although the Council of Trent declared the Bible inspired "in all its parts ",3 yet this guarantee of inerrancy applies not to these parts taken in "proof-texting" iso1 For a collection of current essays on this subjects see Charles E. Curran and Richard A. McCormick, S.J., eds. The Use of Scripture mMoral Theology (Readings in Moral Theology, No. 4) (New York: Paulist Press, 1984) and Robert J. Daly, S.J., et al. Christian Biblical Ethics from Biblical Revelation to Contemporary Christian Praxis, Method and Content (New York: Paulist Press, 1984) for a more systematic argument. For my own position see, "The Development of Doctrine about Sin, Conversion, and the Following of Christ" in Moral Theology Today: Certitudes and Doubts (St. Louis: Pope John Center, 1984) p. 46-64. 2 See Brevard S. Childs, The New Testament as Canon (Philadelphia: Fortress Press, 1984), pp. 3-47. 3 Council of Trent, Session IV, DS 1504, Vatican II, Dei Verbum, n. 11. 501 502 BENEDICT M. ASHLEY, O.P. lation nor merely in their context within a given book of the Bible, but in their ultimate context within the total Canon. Consequently, seriously to view the Bible from the perspective of a " historicist " rather than a " classical world view " (as Bernard Lonergan urged us to do 4) we must not leave the concrete moral teaching of the Scripture on the shelf of the pa.st. Instead let's use a hermeneutic by which God's Word revealed in history truly illuminates today's problems. Scripture and the Construction of the Human Person Today we are concerned about problems of artificial human reproduction and of genetic engineering. Does the Bible cast any light on these puzzles? To ask about reconstructing humans, we must first ask how God constructed them. Through much of its history Catholic theology read the Bible through the eyes of Platonism because this seemed to make the Gospel intelligible and credible to the Greco-Roman world. Perhaps it was this Platonic theology that Lonergan was thinking about when he spoke of " the classical worldview " with its neglect of human historicity. Platonism helped theology defend the "primacy of the spiritual" and especially the dignity and immortality of the human spirit. But it also favored a non-biblical dualism which identified the true human person with the soul and considered the body as its tomb.5 If we shelve this Platonic theology and seek a less dualistic, more historicist anthropology, we discover the first chapters of Genesis wonderfully provide such an anthropology as the basis of a moral Instruction or Torah.6 This Torah forms the cove4 Bernard Lonergan, "The Transition from a Classicist World-View to Historical Mindedness" (1966) in Second Collection, ed. by W. F. K. Ryan and B. J. Tyrrell (London: Darton, Longmans, Todd, 1974), pp. 1-9. 5 For an extensive discussion of this history see my Theologies of the Body: Humanist and Christian (Braintree, Mass.: Pope John Center, 1985), pp. 101250. 6 Isaac M. Kikawanda and Arthur Quinn, Before Abraham Was (Nashville, Tenn.: Abngidon Press, 1985), discounting the Documentary Hypothesis not from a conservative but from an advanced literary point of view, have pro- CONSTRUCTING/RECONSTRUCTING THE HUMAN BODY 503 nant foundation of both Old and New Testament around which the whole Canon takes... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:GENDER AND THE PRIESTHOOD OF CHRIST: A THEOLOGICAL REFLECTION BENEDICT M. ASHLEY, 0.P. Aquinas Institute of Theology St. Louis, Missouri I. Does "Patriarchy" Explain the Tradition? HE CONGREGATION for the Doctrine of the Faith, n its 1976 Declaration on the Question of the Admission f Wonien to the Ministerial Priesthood, based its negative response primarily on tradition.1 For many this argument 1 Inter Insigniores (Oct. 15, 1976, AAS (...) 69 [1977]), Origins 6, 33 (Feb. 3, 1977) : 518-531. For a general bibliography on women's studies see Patricia K. Ballou, Women: A Bibliography of Bibliographies, 2nd ed. (Boston: G. K. Hall, 1986). For select bibliography pro and con on the present topic see note 92, p. 560 of my Theologies of the Body: Humanist and Christian (St. Louis: Pope John Center, 1985) and Wendell E. Langley, S.J. and Rosemary J ermann, " Women and the ministerial priesthood: An annotated bibliography," Theology Digest 29 :329-42 (Winter '81). Strong cases against ordination are made by Louis Bouyer, W onzan in the Church, tr. by Marilyn Techert [Epilogue by Hans Urs von Balthasar and Essay by C. S. Lewis, "Priestesses in the Church"] (San Francisco: Ignatius Press, 1979) ; Manfred Hauke, Women in the Priesthood? A Systematic Analysis in the Light of the Order of Creation and Redemption, tr. by David Kipp (San Francisco: Ignatius Press, 1988); L. Ligier, "Women and the ministerial priesthood," Origins, 7:694-702 (April 20, 1978); and Patrick Dunn, Priesthood: A Re-Examination of the Roman Catholz'.c Theology of the Presbyterate (Staten Island, NY: Alba House, 1990), pp. 173-196. Strong cases for ordination are made by Ida Raming, The Exclusion of Women from Priesthood: Divine Law or Sex Discrimination, tr. by Norman R. Adams (Meutchen, NJ: Scarecrow Press, 1976) ; Haye von der Meer, Women Priests in the Catholic Chitrch: A Theological -Historical Investigation, tr. by Arlene and Leonard Swidler (Philadelphia : Temple University Press, 1973) ; George Tavard, Woman in Christian Tradition (Notre Dame: University of Notre Dame Press, 1973) ; Karl Raimer, "Priestertum der Frau," Stimmen der Zeit, 195 :291-301 (May 1977) ; Joseph Komonchak, " Theological Questions on the Ordination of Women," Catholic Mind 75 CJan. 1977) : 13-28; Carroll Stuhlmueller, C. P., ed., Women and Priesthood: Future Directions (Collegeville, MN: Liturgical Press, 1978); and Elizabeth Schussler Fiorenza, In Memory of Her: A Feminist Theological Reconstruction of Christian Origins (New York: Crossroad, 1983). 343 344 BENEDICT Mo ASHLEY, OoPo fails to persuade" It seems obvious to them that this " tradition " merely reflects the " patriarchalism " of the Jewish and pagan milieu of the early Church" The Declaration anticipated this objection when it pointed out (a) that Jesus was counter-cultural in many respects, especially in his attitude toward women; (b) a better explanation for the tradition can be found in the reality (res) which the sacrament of ordination symbolizes, namely, that the priest acts ini persona Christi capitis ecclesiae" Thus the essential role of a Christian priest is to represent Christ present and acting in his Church as its male Head" The Congregation formulated its conclusion cautiously: "The Church, in fidelity to the example of the Lord, does not consider herself authorized to admit women to priestly ordination." 2 Thus no other opinion may be followed in practice, and if bishops or theologians raise questions about the meaning of the tradition they must not trivialize its importance nor arouse illusory expectations of change. Final judgment on the matter can only pertain to the magisterium. In what follows I will not explore the argument from tradition as such, but only the supporting argument from symbolism, in an attempt to fill in certain steps which it seems to me the Declaration passed over. Nor will I deal here with other secondary arguments against the Declaration's conclusion, particular the pragmatic argument that since Christians have a right to the Eucharist, the decline of male priestly vocations in many secularized countries justifies the ordination of women" H the Church has no power to ordain women validly, obviously that argument, however practically attractive, is beside the point2 2 Inter Insigniores, last paragraph of the Introduction. 3 The members of a local church have a " right " to the Eucharist only if they... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:SCRIPTURAL GROUNDS FOR CONCRETE MORAL NORMS 1. Is JJ1oral Theology Really Theology? 0 BE CHRISTIAN theology moral theology ought to be firmly grounded in the Bible as understood in the living tradition of the Church. Yet the moralist who asks help from the biblicist today is to be met with a host cf objections.1 I will mention eight I have encountered: l) Attempts to develop a biblical theology unified (...) by some central concept such as promise fulfillrnent, salvation history, or liberation have all broken down. The Bible contains many diverse, even contradictory, or at least dialectically opposed theologies and ethical To harmonize them is to distort them.2 1 See Charles E. Curran and Richard A. McCormick, S.J., eds., The Use of Scriptures in Moral Theology (Readings in Moral Theology No. 4. New York: Paulist, 1984) for a representative selection of essays, and Robert J. DaLy, S.J. in cooperation with.J. A. Fischer, C.M., T. J. Keegan, O.P., A..J. Tambasco, L. J. Topel, S.J., and F. E. Schuele, Christian Biblical Ethfos Ji'rorn Biblical Revelation to Contemporary Christian Praxis, Method and Content {New York: Paulist, 1984) for a more systematic argument.. In these notes these will be referred to as US and CBE. See also William C. Spohn, S.J., What Are '!'hey Saying About Bcriptiire a,nd Ethics? (New York: Paulist, 1983) ; David Kelsey, Uses of Scripture in Recent Theology (Philadelphia : Fortress, 1975); and Bruce C. Birch and Larry Rasmussen, Bible and Ethics in the Christian Life (l\finneapolis: Augsburg, 1976). Valuable hermeneutical suggestions ·will be found in Rudolf Schnackenburg, The Moral Teaching of the New Testarnent (New York: Seabury, 1973) and the two works of Pierre Grelot, Sens Oh1·etien de l'Ancien Testarnent 2nd ed. (Paris: Desclee, 1962) and Problemes de ilforale JJ'ondarnentale: Un eclairar1e biblique (Paris: Cerf, 1982) and the essa\)'s in :M:. Gilbert, J. L'Hour and,J. Scharbet, Morale et Ancien Testament, (Universite Catholique du Louvain, 1976). 2 See H. G. Reventlow, Problems of Old Testament Theology in the Twen· tieth Cent·ury (Philadelphia: Fortress Press, 1985, pp. 44,65; 125-133, and 1 BENEDICT M. ASHLEY, O.P. 2) The predominant literary form of the Bible which holds it together is narrative. How then can we draw moral principles from such narratives? To treat them as cautionary tales with an obvious moral does great injustice to their psychological richness and moral ambiguity.3 3) The Bible primarily uses not a literal but a symbolic type of language appropriate to the mysteries it reveals. These symbols or images can mold ethical attitudes and affections but they cannot be reduced to literal concrete moral norms without danger of distortion.4 4) Granted that both Testaments contain many prescriptive statements, they are so embedded in their historical contexts and so related to situations that are now obsolete, that it is impossible to believe they oblige us today. Can we really believe that women must be veiled (I Cor 11: 10) or that slaves should obey their masters (Ti 2: 9)? 5 5) The early Church, and perhaps Jesus himself, expected the eschaton within a lifetime. Consequently, the New Testament provides only an " interim ethics " which is useless as a guide in a continuing sinful world.6 6) We read in Ephesians 2: 15 that Jesus "in his own flesh John H. Hayes and Frederick Prussner, Old Testament Theology: Its Nature and Development (Atlanta: John Knox, 1985), especially pp. 254-279 for a discussion of the search for a unifying concept for the Bible and its present status. s James A. Fischer, C.M., "Story and Image", CBE, pp. 156-169. 4 CBE, pp. 289-295. 5 Thus James M. Gustafson, in an influential article, "The Place of Scripture in Christian Ethics: A Methodological Study" (US, pp. 151-177) distinguishes the uses of Scripture as moral law, as moral ideal, as moral analogy, and finally what he calls its "loose" use to inspire reflection on current problems. He is especially critical of the first method and gives preference to the last. s" To put the matter most sharply, Jesus does not provide a valid ethics for today. His... (shrink)

"Characterized by breadth of coverage, a refreshingly balanced approach to controversial issues, & a highly readable style."-Theological Studies.

Archival research reports that managers often use the FIN 48 uncertain tax liability accrual to manage earnings. To assess solutions to this problem, we deconstruct the ethical and psychological reasoning that leads to FIN 48 opportunistic behavior. Hence, we employ a survey of seasoned accounting managers to assess the influences of cynicism, two measures of moral disengagement, and pressure from a CFO on the propensity to engage in FIN 48 earnings management. Specifically, we manipulate the influence of the study scenario (...) supervisory CFO as either a latent bully or a transformational leader. While the CFO bully main effect condition enhances FIN 48 earnings management, the CFO transformational leader condition interacts with less cynical accounting managers to reduce FIN 48 earnings management. We also find that both dispositional trait and situational state moral disengagement factors independently mediate the relationship between the cynicism model antecedent and FIN 48 earnings management. Collectively, study findings provide implications for both theory and practice. (shrink)

Do the conditions under which promises are made determine whether they ought to be kept? Philosophers have placed a number of conditions on promising which, they hold, must be met in order to make promise‐keeping obligatory. In so doing, they have distinguished valid promises from invalid promises and justified promises from promises that are not justified. Considering such conditions, one by one, we argue that they are mistaken. In the first place, the conditions they lay down are not necessary for (...) either valid or justified promise‐making. In the second place, promises need not meet such conditions in order to create moral obligations. In general, such analyses of promising fail because they suffer from a confusion between promise‐making and promise‐keeping. Philosophers have wrongly supposed that obligations to keep promises are dependent upon, or derivable from, the quality of the promises themselves, at the time they are made, instead of focusing on conditions that must be satisfied at the time when promises are supposed to be kept. It is not the quality of a promise that determines an obligation to keep it but the rightness or wrongness of performing the promised act. (shrink)

Working from a realist Thomistic epistemology, Ashley asserts that we must begin our search for wisdom in the natural sciences; only then, he believes, can we ensure that our claims about immaterial and invisible things are rooted in reliable experience of the material. Any attempt to share wisdom, he insists, must derive from a context that is both interdisciplinary and intercultural. Ashley offers an ambitious analysis and synthesis of major historical contributions to the unification of knowledge, including non-Western (...) traditions. Beginning with the question "Metaphysics: Nonsense or Wisdom?" Ashley moves from a critical examination of the foundations of modern science to quantum physics and the Big Bang; from Aristotle's theory of being and change, through Aquinas's five ways, to a critical analysis of modern and postmodern thought. Ashley is able to interweave the approaches of the great philosophers by demonstrating their contributions to philosophical thought in a concrete, specific manner. In the process, he accounts for a contemporary culture overwhelmed by the fragmentation of data and thirsting for an utterly transcendent yet personal God. "This is an impressive, well-researched book, of great value. It offers the wider philosophical community a point of entrance, by a proponent of a certain type of Thomism, into a domain that all philosophers think they already understand. The result is the creation of a 'big picture' of human knowledge." -- _Mark Johnson, Marquette University_. (shrink)

Contending that concern over the ethical dimensions of these and other like issues are no longer just in the domain of those involved in medical practice, the ...